We highly praised the ambition, technology and design that has made it possible to easily diagnose TB in developing countries with a 70% sensitivity, which is equivalent to expensive diagnostic equipment. Instead of using sputum samples which are challenging to produce for HIV positive patients whose 40% of death is claimed by TB, the diagnosis kit uses urine to detect low concentrations of a compound specifically produced by TB. The utilization of silver amplification technology, which is now considered nonessential, has reminded us the importance of discovering new things by taking lessons from the past.